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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPX2
All Species:
24.85
Human Site:
S654
Identified Species:
54.67
UniProt:
Q9ULW0
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW0
NP_036244.2
747
85653
S654
V
A
E
G
L
S
G
S
L
V
Q
E
P
F
Q
Chimpanzee
Pan troglodytes
XP_001153533
746
85517
S653
V
A
E
G
L
S
G
S
L
V
Q
E
P
F
Q
Rhesus Macaque
Macaca mulatta
XP_001109645
746
85683
S653
V
A
E
G
L
S
G
S
L
V
Q
E
P
F
Q
Dog
Lupus familis
XP_850934
748
86144
S655
I
A
E
G
L
S
G
S
L
V
Q
E
P
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_082385
745
85876
S653
L
A
E
N
P
S
G
S
L
V
Q
E
P
F
Q
Rat
Rattus norvegicus
NP_001101260
744
85432
S652
A
A
E
N
P
S
G
S
L
V
Q
E
P
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516385
623
69684
G573
V
S
S
P
A
L
R
G
R
R
A
G
P
D
H
Chicken
Gallus gallus
NP_989768
739
85048
E653
L
S
V
P
E
N
F
E
L
A
T
E
K
R
A
Frog
Xenopus laevis
NP_001086751
715
81991
S622
L
T
D
S
L
S
G
S
M
I
Q
E
G
F
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798362
948
108486
D861
L
T
E
I
D
A
F
D
L
N
T
D
R
R
A
Poplar Tree
Populus trichocarpa
XP_002327911
811
91572
A758
R
R
T
M
V
P
H
A
R
P
V
P
N
F
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.5
90.3
N.A.
79.2
79.1
N.A.
40.1
57.5
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
98.6
93.9
N.A.
87.6
87.4
N.A.
53
72.5
70
N.A.
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
13.3
13.3
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
20
33.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
55
0
0
10
10
0
10
0
10
10
0
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
10
0
0
0
10
0
10
0
% D
% Glu:
0
0
64
0
10
0
0
10
0
0
0
73
0
0
10
% E
% Phe:
0
0
0
0
0
0
19
0
0
0
0
0
0
73
0
% F
% Gly:
0
0
0
37
0
0
64
10
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
10
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
37
0
0
0
46
10
0
0
73
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
10
0
0
0
10
0
0
10
0
10
% N
% Pro:
0
0
0
19
19
10
0
0
0
10
0
10
64
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
55
% Q
% Arg:
10
10
0
0
0
0
10
0
19
10
0
0
10
19
0
% R
% Ser:
0
19
10
10
0
64
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
19
10
0
0
0
0
0
0
0
19
0
0
0
0
% T
% Val:
37
0
10
0
10
0
0
0
0
55
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _